What Are Polynucleotides?
Polynucleotides are injectable treatments made from highly purified DNA fragments, usually derived from salmon or trout. They are thought to support the skin’s own repair processes — including hydration, elasticity and collagen production — helping improve skin quality from within.
They are particularly popular for the delicate skin under the eyes, where options are limited, as well as for crepey skin on the face and neck, fine lines and overall texture.
Is It Right for You?
Polynucleotides tend to suit people with thin, crepey or tired-looking skin, under-eye concerns where filler isn’t suitable, or who want a gradual, natural improvement in skin quality.
They are not suitable for anyone with a fish or seafood allergy, and they don’t replace volume or treat expression lines. Evidence for polynucleotides is still developing, so we will give you a balanced view of what they can realistically achieve.
Benefits
- Supports overall skin quality and texture
- A useful option for the under-eye area
- Gradual, natural-looking improvement
- Suitable for face, neck and hands


